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Based on the data mining technology, the rules of acupoint selection and prescription were analyzed for impotence treated with acupuncture and moxibustion in ancient recorded in
Subject(s)
Humans , Male , Acupuncture Points , Acupuncture Therapy , Data Mining , Erectile Dysfunction , Meridians , Moxibustion , TechnologyABSTRACT
@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To study the characteristics and related influencing factors of subfoveal choroidal thickness(SFCT)changing with time in children with myopia. <p>METHODS: Totally 60 eyes of 60 children with myopia aged 6-15 years old who were admitted to the Eye Hospital of Nanchang University from July 2018 to September 2018 were included. IOP, axial length, equivalent spherical degree and SFCT were measured at baseline and 6mo of follow-up, respectively. Analyze the changes of the above-mentioned eye parameters and related influencing factors of SFCT. <p>RESULTS: Compared with baseline, follow-up for 6mo, myopic children's SFCT decreased by 8±14μm(<i>P</i><0.001), the axial length increased by 0.15±0.16mm(<i>P</i><0.001), and the equivalent spherical degree increased by -0.34±0.33D(<i>P</i><0.001), and there is a significant correlation between the SFCT change value and the axial length and equivalent spherical power change value(<i>r</i>s=-0.701, 0.633, both <i>P</i><0.001), indicating faster axial growth and myopia increasing is related to more thinning of the membrane thickness. Multiple linear regression analysis shows that SFCT is significantly correlated with axial length(<i>P</i>=0.001).<p>CONCLUSION: The SFCT of myopic children becomes thinner over time, and the axial length is negatively correlated with SFCT, and children with faster axial growing and greater myopia increasing are usually accompanied by more SFCT thinning.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To study the characteristics and related influencing factors of subfoveal choroidal thickness(SFCT)changing with time in children with myopia. <p>METHODS: Totally 60 eyes of 60 children with myopia aged 6-15 years old who were admitted to the Eye Hospital of Nanchang University from July 2018 to September 2018 were included. IOP, axial length, equivalent spherical degree and SFCT were measured at baseline and 6mo of follow-up, respectively. Analyze the changes of the above-mentioned eye parameters and related influencing factors of SFCT. <p>RESULTS: Compared with baseline, follow-up for 6mo, myopic children's SFCT decreased by 8±14μm(<i>P</i><0.001), the axial length increased by 0.15±0.16mm(<i>P</i><0.001), and the equivalent spherical degree increased by -0.34±0.33D(<i>P</i><0.001), and there is a significant correlation between the SFCT change value and the axial length and equivalent spherical power change value(<i>r</i>s=-0.701, 0.633, both <i>P</i><0.001), indicating faster axial growth and myopia increasing is related to more thinning of the membrane thickness. Multiple linear regression analysis shows that SFCT is significantly correlated with axial length(<i>P</i>=0.001).<p>CONCLUSION: The SFCT of myopic children becomes thinner over time, and the axial length is negatively correlated with SFCT, and children with faster axial growing and greater myopia increasing are usually accompanied by more SFCT thinning.
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@#AIM: To study the characteristics and related influencing factors of subfoveal choroidal thickness(SFCT)changing with time in children with myopia. <p>METHODS: Totally 60 eyes of 60 children with myopia aged 6-15 years old who were admitted to the Eye Hospital of Nanchang University from July 2018 to September 2018 were included. IOP, axial length, equivalent spherical degree and SFCT were measured at baseline and 6mo of follow-up, respectively. Analyze the changes of the above-mentioned eye parameters and related influencing factors of SFCT. <p>RESULTS: Compared with baseline, follow-up for 6mo, myopic children's SFCT decreased by 8±14μm(<i>P</i><0.001), the axial length increased by 0.15±0.16mm(<i>P</i><0.001), and the equivalent spherical degree increased by -0.34±0.33D(<i>P</i><0.001), and there is a significant correlation between the SFCT change value and the axial length and equivalent spherical power change value(<i>r</i>s=-0.701, 0.633, both <i>P</i><0.001), indicating faster axial growth and myopia increasing is related to more thinning of the membrane thickness. Multiple linear regression analysis shows that SFCT is significantly correlated with axial length(<i>P</i>=0.001).<p>CONCLUSION: The SFCT of myopic children becomes thinner over time, and the axial length is negatively correlated with SFCT, and children with faster axial growing and greater myopia increasing are usually accompanied by more SFCT thinning.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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@#AIM: To investigate the vision-related quality of life after corneal refraction surgery of the new recruits in a navy unit. <p>METHODS:New recruits in a navy unit during 2014-2016 were interviewed druing recheck ophthalmic examination through a questionnaire, including basic data and the Visual Function Questionnaire-25(VFQ), and also checking the visual acuity, contrast sensitivity(CS), optometry.<p>RESULTS: Among 2 760 new recruits, 340 persons(12.32%)had undergone corneal refractive surgeries, which included corneal stroma surgery(89.71%)and corneal surface surgery(10.29%). According to the preoperative myopia spherical equivalent, the subjects were divided into three groups: mild myopia group(≤-3.00D, 134 cases), moderate myopia group(>-3.00 D to < -6.00D, 159 cases), and high myopia group(≥-6.00D, 47 cases). The postoperation spherical equivalent range ±1.0D is 128 cases(95.52%), 153 cases(96.23%), 38 cases(80.85%)in mild myopia group, moderate myopia group and high myopia group respectively. The contrast sensitivity(CS)were statistically significant among three different diopter groups under natural light and glare conditions(<i>P</i><0.05), the CS of the low myopia group and moderate myopia group were higher than in high myopia group(<i>P</i><0.05). The visual-related quality of life scores were statistically significant among three group(<i>P</i><0.05). The scores of low(6.25±8.61)points and moderate myopia groups(6.87±8.51)points were significantly better than that of high myopia group(9.84±9.76)points(<i>P</i><0.05).<p>CONCLUSION:The vision-related quality of life in new recruits after corneal refractive surgery in the unit is related with preoperative diopter of refractive error. The vision-related quality of life in recruit with lower diopter are better than in recruit with higher dioper.
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The application of special acupoints for different primary symptoms of chronic gastritis in ancient literature of acupuncture and moxibustion was analyzed and summarized. With keywords, electronic and manual retrieval of ancient literature being performed to establish a database, the association rules were performed with SPSS Modeler 18. As a result, ① among all the 2243 items included, 109 items mentioned special acupoints (excluding those only mentioned crossing acupoint). The frequency of special acupoints was 2554 (71.7%), and the special acupoints on the spleen meridian, the stomach meridian, the conception vessel were frequently used. The frequency of five- point was highest, followed by front- points. ② The special acupoints for four main primary symptoms of chronic gastritis, "stomachache" "vomiting and regurgitation" "belching and acid regurgitation" and "epigastric fullness", included Zusanli (ST 36), Neiguan (PC 6), Zhongwan (CV 12), Gongsun (SP 4), Taibai (SP 3). In addition, the back- points were also selected to treat the primary symptoms other than "epigastric fullness". Zhangmen (LR 13) was added to treat "belching and acid regurgitation". The combination of Neiguan (PC 6) and Gongsun (SP 4) showed the strongest correlation; due to different primary symptoms, the combination had different emphasis.
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Objective To investigate the content of Calpain in H2O2-induced oxidative stress in cultured human retinal pigment epithelium (RPE) and the change of biologic activity of RPE cells.Methods Normal culture of human RPE cell line (ARPE19 cells) was assigned as the control group,while cells were cultured in the medium with 10 μmol · L-1 and 100 μmol · L-1 H2O2 were the experimental groups.After culture of 4 h,8 h,16 h,32 h,the proliferation rate of RPE cells induced with different concentrations of H2 O2 was measured by methyl thiazolyl tetrazolium (MTT) assay,and the Ca2 + concentration was measured with fluorescence dye Fluo-3/AM ester,laser scanning confocal microscopy (LSCM) and flow cytometry.Then irritation with 10 μmol ·L-1 H2 O2 for 8 hours,Calpain protein and mRNA in RPE cells were detected by WesternBlot and RT-PCR.Results The proliferation rates (r) of the RPE cells were increased significantly induced by 10 μmol · L-1 H2O2 for 4 h,8 h,16 h and 100 μmol ·L-1 H2 O2 for 4 h,8 h when compared with the control group,and the differences were statistically significant (all P ＜ 0.01),whereas the rates of the cells induced by 100 μ mol · L-1 H2O2 for 16 h and 32 h were less than those of the control group (all P ＜0.01).The Ca2+ concentration in RPE cells induced by 10 μmol · L-1 H2O2 for 8 h was significantly higher than that in the controls [(563.27 ± 77.10) U vs.(170.77 ± 20.11) U] (P ＜ 0.01),and the protein and mRNA levels of Calpain were significantly increased when compared with the control group (both P ＜ 0.05).However,these changes can be effectively suppressed using Calpain inhibitor SNJ-1945 (SNJ).Conclusion The Ca2+ inflow can make Calpain activation involve in oxidative stress stimulated by a certain concentration of H2 O2 in RPE cells.
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<p><b>OBJECTIVE</b>To analyze the clinical features and prognostic factors of patients with mantle cell lymphoma(MCL).</p><p><b>METHODS</b>The clinical data of 66 MCL patients were collected from the Department of Hematology of Shanghai Ruijin Hospital, Shanghai Jiaotong University Medical School from January 2000 to December 2014. The clinical characteristics, treatment efficiency and survival rate were analyzed retrospectively.</p><p><b>RESULTS</b>The sex ratio of male to female in these 66 MCL patients was 3.71:1, the nosopoietic median age was 59 years old, and most cases were diagnosed as MCL in Ann Arbor stage III-IV(90.9%). "R-HperCVAD" regimen had the highest CR-rate reached to 55.6%, and CR rate of "R-CHOP" reached to 44.4%. The total prospective 5-year overall survival and progress-free survival rates were 35.5%±11.5% and 8.8%±5.6%, respectively. Leukocyte count abnormality(>10×10/L or <4×10/L), B symptom, LDH level, bone marrow involvement, Ki-67 and high risk group of MIPI scores, and therapy combined with or without rituximab were the independent prognostic factors.</p><p><b>CONCLUSION</b>The prognosis of MCL patients is poor, and the incidence is higher in men. The extranodal sites of bone marrow and gastrointestinal tract are involved more easily. The treatment combined with rituximab can increase survival rate for these patients.</p>
ABSTRACT
?AIM:To study the clinical value of non-steroidal anti-inflammatory drug in adjuvant treatment of intravitreal triamcinolone acetonide ( IVTA ) for macular edema caused by retinal vein occlusion ( RVO) .?METHODS: Forty - eight eyes in 48 patients were randomly divided into trial and control group ( 24 eyes each ) in this prospective study. In the trial group, additional pranoprofen drops was administered from 1d before IVTA to 30d after injection. Central foveal thickness ( CFT ) was measured with optical coherence tomography ( OCT ) . Available documents of best corrected visual acuity ( BCVA ) , CFT, intraocular pressure and complications pre- and post-injection at 3d, 1,2wk, 1 and 3mo were evaluated.?RESULTS: After IVTA, BCVA was improved in both groups at different levels; but there was no statistically significant between two groups at each time point ( P>0. 05). The CFT values were 629 ± 43μm vs 605 ± 57μm before IVTA in the trail vs control groups (P>0. 05). The values were 432±74μm vs 511±32μm (t=7. 533, P<0. 05), and 275±54μm vs 379±29μm (t=13. 212, P<0. 05) of the trial vs control groups at 1 and 3mo after IVTA, respectively. Ocular hypertension occurred in 5 eyes after injection in trail group, and was controlled with anti-glaucoma medication and one eye with filtration surgery. Progression of cataract was noted in 3 of 35 phakic eyes and cataract surgery was performed in 2 eyes at 4-12mo after injection in trail group. Progression of cataract was noted in 4 eyes and cataract surgery was performed in 2 eyes at 4- 12mo after injection in control group. No retinal detachment and endophthalmitis happened during the whole period of follow-up.?CONCLUSION: Application of non - steroidal anti -inflammatory eye drops in perioperative period can be useful to improve the outcome of IVTA for macular edema, which needs further evaluation.